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Merge pull request #2 from ispras/v1.1.0
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added new version of ecglib package
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AvetisyanAram authored Jun 20, 2023
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19 changes: 19 additions & 0 deletions .gitignore
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__pycache__/
.pybuilder/
.ipynb_checkpoints

# Distribution / packaging
.Python
build/
develop-eggs/
dist/
downloads/
eggs/
.eggs/
lib/
lib64/
parts/
sdist/
var/
wheels/
share/python-wheels/
*.egg-info/
.installed.cfg
*.egg
2 changes: 1 addition & 1 deletion MANIFEST.in
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include ecglib/models/weights/*.yaml
include src/ecglib/models/weights/*.yaml
133 changes: 91 additions & 42 deletions README.md
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## Table of contents

- [Introduction](#datasets)
- [Datasets](#datasets)
- [Introduction](#introduction)
- [Credits](#credits)
- [Installation](#installation)
- [Data](#data)
- [Models](#models)
- [Preprocessing](#preprocessing)
- [ToDo](#todo)
- [Credits](#credits)
- [Predict](#predict)

### Introduction

**Ecg** **lib**rary (`ecglib`) is a tool for ECG signal analysis. The library helps with preprocessing ECG signals, downloading the datasets, creating Dataset classes to train models to detect ECG pathologies. The library allows researchers to use model architectures pretrained on more than 500,000 ECG records to fine-tune them on their own datasets.
**Ecg** **lib**rary (`ecglib`) is a tool for ECG signal analysis. The library helps with preprocessing ECG signals, downloading the datasets, creating Dataset classes to train models to detect ECG pathologies and EcgRecord classes to store their records. The library allows researchers to use model architectures pretrained on more than 500,000 ECG records to fine-tune them on their own datasets.

### Credits

If you find this tool useful in your research, please consider citing the paper:

1) **Deep Neural Networks Generalization and Fine-Tuning for 12-lead ECG Classification** - We demonstrate that training deep neural networks on a large dataset and fine-tuning it on a small dataset from another domain outperforms the networks trained only on one of the datasets.

@article{avetisyan2023deep,
title={Deep Neural Networks Generalization and Fine-Tuning for 12-lead ECG Classification},
author={Avetisyan, Aram and Tigranyan, Shahane and Asatryan, Ariana and Mashkova, Olga and Skorik, Sergey and Ananev, Vladislav and Markin, Yury},
journal={arXiv preprint arXiv:2305.18592},
year={2023}
}

### Datasets
This module allows user to load and store ECG datasets in different formats and to extract meta-information about each single ECG signal (i.e. frequency, full path to file, scp-codes, patient age etc.).
### Installation

To install the latest version from PyPI:

```
pip install ecglib
```

### Data
This module allows user to load and store ECG datasets and records in different formats and to extract meta-information about each single ECG signal (i.e. frequency, full path to file, scp-codes, patient age etc.).

Via `load_datasets.py` one can download [PTB-XL ECG database](https://physionet.org/content/ptb-xl/1.0.2/) in its original *wfdb* format and to store information concerning each record in a *csv* file.

```python
# download PTB-XL ECG dataset

from ecglib.datasets import load_ptb_xl
from ecglib.data import load_ptb_xl

ptb_xl_info = load_ptb_xl(download=True)
```

`datasets.py` script contains classes for storing ECG datasets.
- *ECGDataset* is a general class for storing main features of your ECG dataset such as number of leads, number of classes to predict, augmentation etc..
- *PTBXLDataset* is a child class with respect to *ECGDataset*; one can load each record from *wfdb* or *npz* format and preprocess it before further utilization. It is also possible to create a *png* picture of each record using [ecg-plot](https://pypi.org/project/ecg-plot/).
Via `ecg_record.py` one can create class *EcgRecord* to store important information about an ECG record.

```python
# create PTBXLDataset class from PTB-XL map file
# creating EcgRecord class for example file

from ecglib.data import EcgRecord
import wfdb

ecg_signal = wfdb.rdsamp("wfdb_file")[0] # for example 00001_hr from PTB-XL dataset
ecg_record = EcgRecord(signal=ecg_signal.T, frequency=500, patient_id=1)

```

Via `datasets.py` one can create class *EcgDataset* to store ECG datasets. It stores main features of your ECG dataset such as number of leads, number of classes to predict, augmentation etc. It is also possible to plot each record using [ecg-plot](https://pypi.org/project/ecg-plot/).

```python
# create EcgDataset class from
# fit targets for 'AFIB' binary classification

from ecglib.datasets import PTBXLDataset
from ecglib.data import EcgDataset

targets = [[0.0] if 'AFIB' in eval(ptb_xl_info.iloc[i]['scp_codes']).keys() else [1.0]
for i in range(ptb_xl_info.shape[0])]
ecg_data = PTBXLDataset(ecg_data=ptb_xl_info, target=targets)
ecg_data = EcgDataset(ecg_data=ptb_xl_info, target=targets)
```

### Models
This module comprises components of model architectures and open weights for models derived from binary classification experiments in several pathologies.

`create_model` function allows user to create a model from scratch (currently supported architectures include *densenet1d121*, *densenet1d201*) as well as load a pretrained model checkpoint from `weights` folder (currently supported architectures include *densenet1d121*).
`create_model` function allows user to create a model from scratch (supported architectures include *resnet1d18*, *resnet1d50*, *resnet1d101*, *densenet1d121*, *densenet1d201*) as well as load a pretrained model checkpoint from `weights` folder (supported architectures include *resnet1d18*, *resnet1d50*, *resnet1d101*, *densenet1d121*). `create_model` also allows to use both ECG record and metadata during training by concating FCN to the network that takes ECG record as an input.

```python
# create 'densenet1d121' model from scratch for binary classification 12-lead experiment

from ecglib.models import create_model
from ecglib.models.model_builder import create_model

model = create_model(model_name='densenet1d121', pathology='1AVB', pretrained=False)

model = create_model(model_name='densenet1d121', pathology='1AVB', pretrained=False, leads_num=12)
# create 'cnntabular' model with 'densenet1d121' architecture for ECG record and FCN for metadata. Number of input features is set to 5 by default and can be changed by adding config

from ecglib.models.model_builder import Combination
from ecglib.models.config.model_configs import DenseNetConfig, TabularNetConfig

densenet_config = DenseNetConfig()
tabular_config = TabularNetConfig(inp_features=50)
model = create_model(model_name=['densenet1d121', 'tabular'],
config=[densenet_config, tabular_config],
combine=Combination.CNNTAB,
pathology='1AVB',
pretrained=False)
```

```python
# load pretrained 'densenet1d121' model from 'weights' folder for binary classification 12-lead experiment

from ecglib.models import create_model

model = create_model(model_name='densenet1d121', pathology='AFIB', pretrained=True, leads_num=12)
model = create_model(model_name='densenet1d121', pathology='AFIB', pretrained=True)
```

`architectures` folder includes model architectures.

`config` folder contains default parameter dataclasses for building a model.

In `weights` folder one can find file with paths to the models derived from the following binary classification 12-lead experiments. Currently avaliable pathologies (scp-codes): *AFIB*, *1AVB*, *STACH*, *SBRAD*, *RBBB*, *LBBB*, *PVC*, *LVH*.
In `weights` folder one can find file with paths to the models derived from the following binary classification 12-lead experiments. Available pathologies (scp-codes): *AFIB*, *1AVB*, *STACH*, *SBRAD*, *IRBBB*, *CRBBB*, *PVC*.

### Preprocessing
This module includes framework inspired by [Albumentations](https://albumentations.ai/) Python library for preprocessing and augmenting ECG data.

`composition.py` script contains *SomeOf*, *OneOf* and *Compose* structures for building your own preprocessing and augmentation pipeline.

`preprocess.py` and `functional.py` both comprise classes and functions respectively describing different preprocessing and augmentation techniques. For more information see code commentary.
`preprocess.py` and `functional.py` both comprise classes and functions respectively describing different preprocessing and augmentation techniques. You can preprocess either numpy data and EcgRecord data. For more information see code commentary.

```python
# augmentation example
import torch
from ecglib.preprocessing.preprocess import *
from ecglib.preprocessing.composition import *

# provide an ecg-record in `numpy.ndarray` form
ecg_record = read_any_ECG_ndarray_type
# provide an ecg record in a `numpy.ndarray` form
ecg_signal = wfdb.rdsamp("wfdb_file")[0] # for example 00001_hr from PTB-XL dataset
ecg_record = EcgRecord(signal=ecg_signal.T, frequency=500, patient_id=1)

augmented_record = Compose(transforms=[
SumAug(leads=[0, 6, 11]),
RandomConvexAug(n=4),
OneOf(transforms=[ButterworthFilter(), IIRNotchFilter()], transform_prob=[0.8, 0.2])
], p=0.5)(ecg_record)
], p=0.5)(ecg_record) # ecg_signal can be used instead of ecg_record
```

### ToDo
**Next release in December 2022**
- **Datasets**: add support for more data formats and datasets. Change TisDataset/PTBXLDataset to remove duplicates
- **Models**: add more model architectures and weights of these models for different pathologies
- **Preprocessing**: add class ECGrecord and update preprocessing methods
- Add possibility to use metadata for analysis
- Add complex segmentation methods
### Predict
This module allows users to test trained model with the architecture from `ecglib`. You can get the prediction for the specific ECG record or the prediction for all the records in the directory.

### Credits
This project is made possible by:

- [Aram Avetisyan](https://github.com/avetisyanaram) ([email protected])
- [Olga Mashkova](https://github.com/omashkova)
- [Vladislav Ananev](https://github.com/Survial53)
- [Shahane Tigranyan](https://github.com/decoder-99)
- [Ariana Asatryan](https://github.com/arianasatryan)
- [Sergey Skorik](https://github.com/Skorik99)
- [Yury Markin](https://github.com/grandkarabas)
```python
# Predict example
from ecglib.predict import Predict

ecg_signal = wfdb.rdsamp("wfdb_file")[0] # for example 00001_hr from PTB-XL dataset

predict = Predict(
weights_path="/path/to/model_weights",
model_name="densenet1d121",
pathologies=["AFIB"],
frequency=500,
device="cuda:0",
threshold=0.5
)

result_df = predict.predict_directory(directory="path/to/data_to_predict",
file_type="wfdb")
print(predict.predict(ecg_signal, channels_first=False))
```
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