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Updating model tree
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MichaelClerx committed Jul 31, 2024
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## 1997 Endresen mS

## 1998 Courtemanche HA - included
## 1998 Courtemanche HA
**Included**
Courtemanche, Ramirez, Nattel (1998) Ionic mechanisms underlying human atrial action potential properties; insights from a mathematical model
[Paper](https://doi.org/10.1152/ajpheart.1998.275.1.h301)

Expand All @@ -138,13 +139,15 @@ Base: Luo 1994

## 1998 Noble GV

## 1998 Nygren HA - included
## 1998 Nygren HA
**Included**
Nygren, Fiset et al., Giles (1998) Mathematical model of an adult human atrial cell; the role of K-currents in repolarization
[Paper](https://doi.org/10.1161/01.res.82.1.63)

Base: Lindblad 1996

## 1998 Priebe HV - included
## 1998 Priebe HV
**Included**
Priebe, Beuckelmann (1998) Simulation study of cellular electric properties in heart failure
[Paper](https://doi.org/10.1161/01.res.82.11.1206)

Expand Down Expand Up @@ -247,7 +250,8 @@ Bits:
- INaK, IKp, IK1, IpCa from Luo 1994


## 2004 Iyer HV - included
## 2004 Iyer HV
**Included**
Iyer, Mazhari, Winslow (2004) A computational model of the human left-ventricular epicardial myocyte
[Paper](https://doi.org/10.1529/biophysj.104.043299)

Expand All @@ -269,7 +273,8 @@ Modifications:

## 2004 Smith INaK

## 2004 Ten Tusscher HV - included
## 2004 Ten Tusscher HV
**Included**
Ten Tusscher, Noble, Noble, Panfilov (2004) A Model for Human Ventricular Tissue
[Paper](https://doi.org/10.1152/ajpheart.00794.2003)

Expand All @@ -296,7 +301,8 @@ Kurata, Hisatome, Matsuda, Shibamoto (2005) Dynamical Mechanisms of Pacemaker Ge
## 2006 Sato CV
## 2006 Simitev HA

## 2006a Ten Tusscher HV - included
## 2006a Ten Tusscher HV
**Included**
Ten Tusscher, Panfilov (2006) Alternans and spiral breakup in a human ventricular tissue model
[Paper](https://doi.org/10.1152/ajpheart.00109.2006)

Expand Down Expand Up @@ -326,7 +332,8 @@ Faber, Silva, Livshitz, Rudy (2007) Kinetic Properties of the Cardiac L-Type Ca
[Paper](https://doi.org/10.1529/biophysj.106.088807)
[Original code](https://rudylab.wustl.edu/code-downloads/)

## 2007 Livshitz CV - included
## 2007 Livshitz CV
**Included**
Livshitz, Rudy (2007) Regulation of Ca and electrical alternans in cardiac myocytes; role of CAMKII and repolarizing currents
[Paper](https://doi.org/10.1152/ajpheart.01347.2006)
[Original code](https://rudylab.wustl.edu/code-downloads/)
Expand All @@ -342,7 +349,8 @@ Bits:
## 2008 Benson CV
## 2008 Bueno-Orovio HV

## 2008 Fink HV - included
## 2008 Fink HV
**Included**
Fink, Noble et al., Giles (2008) Contributions of HERG K current to repolarization of the human ventricular action potential
[Paper](https://doi.org/10.1016/j.pbiomolbio.2007.07.011)

Expand Down Expand Up @@ -370,7 +378,8 @@ Base: Pandit et al. 2001, and Niederer 2006 and Hinch 2004
## 2009a Aslanidi RA
## 2009b Aslanidi CP

## 2009 Decker CV - included
## 2009 Decker CV
**Included**
Base: Hund 2008

[Original code](https://rudylab.wustl.edu/code-downloads/)
Expand All @@ -397,45 +406,52 @@ Livshitz, Rudy (2009) Uniqueness and Stability of Action Potential Models during
Base: Kurata 2002, Shannon 2004
Maltsev, Lakatta (2009) Synergism of coupled subsarcolemmal Ca2 clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model

## 2009 Stewart HP - included
## 2009 Stewart HP
**Included**
Base: Ten Tusscher 2006

## 2009 Tran reduced

## 2010 Grandi HV - included
## 2010 Grandi HV
**Included**
Base: Shannon 2004
Modifications:
- Scaled gK1
- ...

## 2010 Li MV

## 2010 Sampson HP - included
## 2010 Sampson HP
**Included**
Base: Iyer 2004

## 2011 Aslanidi HA
## 2011 Carro HV
## 2011 Corrias RP

## 2011 Grandi-Pandit-Voigt HA - included
## 2011 Grandi-Pandit-Voigt HA
**Included**
Base: Grandi 2010
Modifications:
- Scaled gK1
- ...

## 2011 Heijman CV - included
## 2011 Heijman CV
**Included**
Base: Decker 2009

[Original code](https://rudylab.wustl.edu/code-downloads/)

## 2011 Koivumaki HA - included
## 2011 Koivumaki HA
**Included**
Base: Nygren 1998

## 2011 Pan CP

[Original code](https://rudylab.wustl.edu/code-downloads/)

## 2011 O'Hara HV - included
## 2011 O'Hara HV
**Included**
Base: Hund 2004
Bits:
- INaK from Smith 2004, with reparametrisation
Expand All @@ -456,10 +472,12 @@ J Biomed Sci Eng. 2013;6(12):47-­60.
## 2013 Colman HA
Base: Colman Courtemanche 1998

## 2013 Paci Hi - included
## 2013 Paci Hi
**Included**
Base: Paci 2012

## 2013 Voigt-Heijman HA - included
## 2013 Voigt-Heijman HA
**Included**
Base: Grandi 2011
Modifications:
- Added IKAch (Kneller et al. 2002)
Expand All @@ -471,15 +489,17 @@ Bases: Several! Interesting one to look at

## 2015 Schmidt

## 2016 Gray RV - included
## 2016 Gray RV
**Included**
Base: New!
Gray, Pathmanathan (2016) A Parsimonious Model of the Rabbit Action Potential Elucidates the Minimal Physiological Requirements for Alternans and Spiral Wave Breakup
## 2016 Morotti HA
Base: Grandi-Pandit-Voigt 2011

## 2016 Varela CA

## 2017 Chang 2017 "ORd-cipa-v1" HV - included
## 2017 Chang 2017 "ORd-cipa-v1" HV
**Included**
Base: O'Hara 2011
[Official CellML](https://models.cellml.org/e/4e8/ohara_rudy_cipa_v1_2017.cellml/view)

Expand All @@ -489,17 +509,20 @@ Base: Colman 2013
## 2017 Ellinwood
## 2017 Fabbri

## 2017 Ni HA - included
## 2017 Ni HA
**Included**
Base: Colman 2017
Bits:
- Calcium subspaces based on Koivumaki 2011

## 2018 Paci Hi - included
## 2018 Paci Hi
**Included**
Base: Paci 2013
Paci, Polonen et al., Hyttinen (2018) Automatic optimization of an in silico model of human iPSC derived cardiomyocytes recapitulating calcium handling abnormalities
## 2018 Sutanto HA

## 2019 Kernik Hi - included
## 2019 Kernik Hi
**Included**
Bases: Shannon 2004, Ten Tusscher 2004, Maltsev 2009
Kernik, Morotti et al., Clancy (2019) A computational model of induced pluripotent stem‐cell derived cardiomyocytes incorporating experimental variability from multiple data sources

Expand All @@ -514,7 +537,8 @@ Base: O'Hara 2011
Bartolucci, Passini et al., Severi (2020) Simulation of the effects of extracellular calcium changes leads to a novel computational model of human ventricular action potential with a revised calcium handling
[Paper](https://doi.org/10.3389/fphys.2020.00314)

## 2020 Paci Hi - included
## 2020 Paci Hi
**Included**
Paci, Passini et al., Entcheva (2020) All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug Evaluation
[Paper](https://doi.org/10.1016/j.bpj.2020.03.018)

Expand All @@ -527,15 +551,17 @@ Tomek, Bueno-Orovio, Rodriguez (2020) ToR-ORd-dynCl; an update of the ToR-ORd mo

Base: Tomek 2019

## 2020 Trovato HP - included
## 2020 Trovato HP
**Included**
[Trovato, Passini et al., Rodriguez (2020) Human Purkinje in silico model enables mechanistic investigations into automaticity and pro-arrhythmic abnormalities](https://doi.org/10.1016/j.yjmcc.2020.04.001)

Base: O'Hara 2011 (HV) and Pan 2011 (CP)

Modifications (partial):
- INa from Dutta 2017; Passini 2016

## 2021 Akwaboah Hi - included
## 2021 Akwaboah Hi
**Included**
Base: Kurata 2002 and Courtemanche 1998
Bits:
- INa from Luo 1991, with partial reparameterisation
Expand All @@ -559,24 +585,24 @@ Gaur, Qi et al., Vigmond (2021) A computational model of pig ventricular cardiom
[Paper](https://doi.org/10.1371/journal.pcbi.1009137)

## 2022 Bartolucci HV
Bartolucci, Forouzandemehr, Severi, Paci (2022) A Novel In Silico Electromechanical Model of Human Ventricular Cardiomyocyte
Base: [O'Hara 2011](#ohara-2011-hv)
[Paper](https://doi.org/10.3389/fphys.2022.906146)
Bartolucci, Forouzandemehr, Severi, Paci (2022) A Novel In Silico Electromechanical Model of Human Ventricular Cardiomyocyte

Base: O'Hara 2011
CODE AVAILABLE, ORG CELLML AVAILABLE

See also? Mazhar, Regazzoni et al., Severi (2022) A Novel Human Atrial Electromechanical Cardiomyocyte Model with Mechano-Calcium Feedback Effect


## 2022 Kohjitani Hi
Kohjitani, Koda et al., Kimura (2022) Gradient-based parameter optimization method to determine membrane ionic current composition in human induced pluripotent stem cell-derived cardiomyocytes
Base: [Himeno 2015](#2015-himeno-hv)
[Paper](https://doi.org/10.1038/s41598-022-23398-0)
Kohjitani, Koda et al., Kimura (2022) Gradient-based parameter optimization method to determine membrane ionic current composition in human induced pluripotent stem cell-derived cardiomyocytes

Base: Himeno 2015

## 2022 Moise
Moise, Weinberg (2022) Emergent Electrical Activity, Tissue Heterogeneity, and Robustness in a Calcium Feedback Regulatory Model of the Sinoatrial Node
[Paper](https://doi.org/10.1016/j.bpj.2023.03.024)
Moise, Weinberg (2022) Emergent Electrical Activity, Tissue Heterogeneity, and Robustness in a Calcium Feedback Regulatory Model of the Sinoatrial Node



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