[NTR]L4 IT (Mus MOp)

[shawntanzk]

Note - please check that the term does not already exist (check OLS: https://www.ebi.ac.uk/ols/ontologies/cl)

Preferred term label:
L4 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus)

Synonyms
L4 IT MOp (Mus)

Definition (free text, please give PubMed ID in format PMID:XXXXXX)
An intratelencephalic-projecting glutamatergic neuron that is located in the boundary between L2/3 and L5 of the primary motor cortex. These cells have diverse morphologies with some pyramidal and some stellate cells.
PMID:33184512

Parent cell type term (check the hierarchy here https://www.ebi.ac.uk/ols/ontologies/cl):
glutamatergic neuron

What is the anatomical structure that the cell is a part of? Please check Uberon: https://www.ebi.ac.uk/ols/ontologies/uberon
http://purl.obolibrary.org/obo/UBERON_0001384 - Primary Motor Cortex
*has some soma location, can specify layer

Your nano-attribution (ORCID)

Any additional notes or concerns
xref:(ILX:0770172)
Subclass of L2/3-6 IT projecting neuron #878

[shawntanzk]

Not sure if I should include the following information:

Likely corresponded to the quasi-L4 neurons described previously in the motor cortex. PMID:25525751.

The paper quoted also writes: (1) input of primary thalamocortical (TC) axons from VL and PO; (2) output to excitatory neurons in other layers, especially L2/3; (3) largely unidirectional L4→2/3 projections (i.e., little input in return from L2/3), and often, although not as a strict rule, (4) a paucity of long-range corticocortical inputs and outputs.

[dosumis]

PCL for now

[shawntanzk]

migrated to obophenotype/brain_data_standards_ontologies#226