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various updates to sweep pipeline #116

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@mufernando mufernando commented Jun 3, 2024

Various edits related to the production run of the sweep pipeline.

  • Changes to the SLURM oregon profile to make Snakemake play nice with the huge load of sims
  • Increase in number of replicates per param (from 200 sims to 1000)
  • Update in diploSHIC (new Keras version)
  • Fixed a bug in diploSHIC training
  • Changed training params in diploSHIC so that the training is not too far from the simulated data (with stdpopsim) -- this can be diagnosed with the pca_sims_training.ipynb
  • Changes to resource usage in some rules
  • write_vcf part of the pipeline had to be adapted to deal with infinite sites assumption (bumping variants at 0 to position 1; removing variants that may happen at last position after rounding).

@mufernando mufernando changed the title Diplo stats various updates to sweep pipeline Jun 3, 2024
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is this ready to merge?

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