Update stdpopsim/catalog/HomSap/dfes.py

Co-authored-by: Peter Ralph <[email protected]>
popsim-consortium · Aug 18, 2023 · dd5b1a8 · dd5b1a8
1 parent f3ddaa7
commit dd5b1a8
Showing 1 changed file with 2 additions and 4 deletions.
diff --git a/stdpopsim/catalog/HomSap/dfes.py b/stdpopsim/catalog/HomSap/dfes.py
@@ -182,12 +182,10 @@ def _KyriazisDFE():
         distribution_type="g",  # gamma distribution
         distribution_args=[gamma_mean, gamma_shape],
     )
-    h = 0
-    s = -1
     lethal = stdpopsim.MutationType(
         distribution_type="f",  # fixed value
-        distribution_args=[s],
-        dominance_coeff=h,
+        distribution_args=[-1],  # fitness in SLiM for homozygotes is multiiplied by 1+ s
+        dominance_coeff=0,
     )
     proportion_deleterious = 0.7  # ratio 2.31:1
     lethal_prop = proportion_deleterious * 0.003  # 0.03% lethals