different neutral prop

stdpopsim/catalog/HomSap/dfes.py

@@ -188,17 +188,10 @@ def _KyriazisDFE():
         distribution_args=[s],
         dominance_coeff=h,
     )
-    # To get 0.63 deleterious mutations per 30Mb diploid coding sequence using
-    # mu from catalog, we need a deleterious proportion of:
-    proportion_deleterious = 0.63 / (3e7 * _species.genome.mean_mutation_rate * 2)
-
-    # Next, 0.03% of deleterious are lethals:
-    gamma_prop = proportion_deleterious * 0.997
-    lethal_prop = proportion_deleterious * 0.003
-    neutral_prop = 1 - gamma_prop - lethal_prop
-
-    # To get 0.63 deleterious mutations per 30Mb diploid coding sequence with
-    # mu=1.29e-8 (current mu from catalog), we need a proportion of 0.8139535:
+    proportion_deleterious = 0.7  # ratio 2.31:1
+    lethal_prop = proportion_deleterious * 0.003  # 0.03% lethals
+    gamma_prop = proportion_deleterious - lethal_prop
+    neutral_prop = 1 - proportion_deleterious
     return stdpopsim.DFE(
         id=id,
         description=description,