Global Biobank Engine

A framework for exploring and sharing genetic data from large genetic datasets.

For full description to setup MongoDB environment see README.md mongodb/

For full description to setup SciDB environment see README.md scidb/

Additional GBE Github repositories

1. Multiple Rare variants and Phenotypes framework, MRP and pre-print
2. MultiVariate Polygenic Mixture Model, MVPMM and paper in American Journal of Human Genetics
3. Multiple Rare variants and Phenotypes Mixture Model, MRPMM
4. snpnet and paper in PLoS Genetics
5. sparse-snpnet and snpnet-2.0 with selective inference and paper in Bioinformatics
6. snpnet-Cox and paper in Biostatistics
7. multiSnpnet Fast Multi-Phenotype Sparse Reduced Rank Regression on Genetic Data and pre-print
8. multiSnpnet-Cox, mrcox Efficient Group-Sparse Lasso solver for multi-response Cox model and paper in Bioinformatics
9. multiSnpnet-Cox-gpu GPU version of multiSnpnet-Cox
10. multiSnpnet-Cox-tv, Coxtv Regularized Cox proportional hazard model with time-varying covariate
11. regularizedMR Regularized Mendelian randomization
12. cGAUGE: Causal Graphical Analysis Using GEnetics and paper in Nature Communications
13. DEcomposition of Genetic ASsociations and paper in Nature Communications
14. DeGAs-risk scores and paper in European Journal of Human Genetics
15. Sex-specific Effects Mixture Model and paper in European Journal of Human Genetics
16. Genetics of 35 blood biomarkers and multiPRS and paper in Nature Genetics