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43 changes: 43 additions & 0 deletions docs/_data/alumni_members.yml
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- name: Daniel M. Low
photo: ../images/daniel_low_lo_fi.png
info: PhD Student
email: [email protected]
duration: 2019 - 2024
number_educ: 2
education1: MA Language & Communication Technologies, University of Groningen
education2: MS Cognitive Science, CIMeC, University of Trento

- name: Gasser Elbanna
photo: ../images/Gasser.png
info: PhD Student
email: [email protected]
duration: 2022 - 2024
number_educ: 2
education1: M.Sc. in Neuroscience and Neuroengineering, EPFL
education2: B.Sc. in Systems and Biomedical Engineering, Cairo University

- name: Sabeen Lohawala
photo: ../images/sabeen.png
info: MEng Student, MIT
email: [email protected]
duration: 2023 - 2024
number_educ: 2
education1: MEng in Computer Science, MIT
education2: B.S. in Computer Science, MIT

- name: Ahmed Zain
photo: ../images/ahmed_zain.jpeg
info: Undergraduate Researcher
email: [email protected]
duration: 2023 - 2024
number_educ: 1
education1: B.S. in Computer Science and Engineering, MIT

- name: Agathe Tournant
photo: //scholar.googleusercontent.com/citations?view_op=view_photo&user=cwcd3BIAAAAJ&citpid=2
info: Visiting M.S. student from ETH Zurich
email: [email protected]
duration: 2023 - 2024
number_educ: 1
education1: B.S. in Physics, EPFL

- name: Alicia Zhang
photo: ../images/alicia_zhang_photo.jpg
info: Undergraduate Researcher
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36 changes: 36 additions & 0 deletions docs/_data/news.yml
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- date: 2024 05 30
headline: >
A paper published on detecting vocal fold paralysis from acousting recordings and
understanding sources of bias in recordings.
<a href="https://journals.plos.org/digitalhealth/article?id=10.1371/journal.pdig.0000516">Paper link</a>
- date: 2024 05 01
headline: >
Welcome Jordan Wilke.
- date: 2024 05 17
headline: >
Congrats to Sabeen for successfully submitting her thesis.
- date: 2024 04 30
headline: >
Congrats to Daniel for successfully defending his
<a href="https://drive.google.com/file/d/1R-u9r-47doN5w6t058K46GEPvKAG4_D-/view?usp=sharing">thesis</a>.
- date: 2024 04 12
headline: >
Congrats to Agathe for successfully presenting her
<a href="https://drive.google.com/file/d/173hwVU2LQf3pqaXti9ynsi1UOIxa_Kyh/view?usp=sharing">thesis</a>.
- date: 2024 04 01
headline: >
Welcome Isaac Bevers.
- date: 2024 03 16
headline: >
Welcome Tek Raj Chhetri.
- date: 2024 02 05
headline: >
Welcome Miles Silva.
- date: 2024 01 16
headline: >
Welcome Chaitanya Kapoor.
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153 changes: 23 additions & 130 deletions docs/_data/projects.yml
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Expand Up @@ -10,6 +10,21 @@
highlight: 1
news2: <a href="https://github.com/dandi" target="_blank">DANDI on GitHub</a>

- title: "BICAN Knowledgebase for neuroscience"
image: https://static.wixstatic.com/media/c57c96_fa6f08e1e79240838d786b6b1b8d5842~mv2.png/v1/fill/w_576,h_324,al_c,lg_1,q_85,enc_auto/Image-empty-state.png
description: >
Develop an extensible Brain Cell Knowledge Base (BCKB) to ingest and standardize c
omprehensive cell type information from BICAN's development of a multimodal,
multi-species brain cell atlas and disseminate that atlas as an open and interactive
community resource for advancing knowledge of the brain. Supported by NIMH 1U24MH130918
(PI: Mufti, Hawrylycz, Ng, and Ghosh).
authors: BICAN team (Allen Institute for Brain Science, MIT)
link:
url: https://beta.brainkb.org
display: Project website.
highlight: 1
news2: <a href="https://github.com/brain-bican" target="_blank">BICAN on GitHub</a>

- title: "Nobrainer: A Robust And Validated Neural Netwrok Tool Suite For Imagers"
image: https://github.com/neuronets/trained-models/raw/master/images/brain-extraction/unet-best-prediction.png
description: >
Expand All @@ -23,18 +38,6 @@
highlight: 1
news2: <a href="https://github.com/neuronets" target="_blank">Neuronets on GitHub</a>

- title: "Nipype: Dataflows for Reproducible Biomedical Research"
image: //miykael.github.io/nipype_tutorial/static/images/nipype_architecture.png
description: >
A Python-based platform for scalable scientific workflow design and execution.
Supported by NIBIB R01 EB020740.
authors: Nipype team
link:
url: https://nipype.readthedocs.io/en/latest/
display: Read more about Nipype
highlight: 1
news2: <a href="https://github.com/nipy/nipype" target="_blank">Nipype on GitHub</a>

- title: "ReproNim: A Center for Reproducible Neuroimaging Computation"
image: http://www.repronim.org/flow.svg
description: >
Expand All @@ -50,18 +53,6 @@
highlight: 1
news2: <a href="https://github.com/repronim" target="_blank">ReproNim on GitHub</a>

- title: "Neuroscout: A cloud-based platform for rapid re-analysis of naturalistic fMRI datasets"
image: https://neuroscout.org/static/Neuroscout_Simple_Wide.svg
description: >
A platform for fast and flexible re-analysis of (naturalistic) fMRI studies.
Supported by NIMH R01 MH109682 (PI: Tal Yarkoni, UTexas, Austin).
authors: Neuroscout team
link:
url: https://neuroscout.org/
display: Neuroscout Website
highlight: 0
news2: <a href="https://github.com/neuroscout" target="_blank">Neuroscout on GitHub</a>

- title: "Naturalistic Parcellation and audiovisual integration"
image: ../images/brain_parcellation.png
description: >
Expand All @@ -73,120 +64,22 @@
highlight: 1
news2:

- title: Voice and language biomarkers of mental health
- title: Voice and language biomarkers of health
image: ../images/review_figure3_heatmap.jpeg
description: >
The goal of this project is to observe and analyze speech variations in psychiatric disorders by analyzing different types of data including ecological momentary assessments, recordings of clinical interviews, and social media posts.
Key questions we hope to answer are: 1) Is speech a good longitudinal biomarker? 2) How much speech information is needed for stable tracking? 3) Can linguistic information augment voice models? 4) Can we create a neurocomputational model of such systems?
authors: Daniel Low
The goal of this project is to observe and analyze speech variations in
across disorders by analyzing different types of data including ecological
momentary assessments, recordings of clinical interviews, and social media posts.
Key questions we hope to answer are: 1) Is speech a good longitudinal biomarker?
2) How much speech information is needed for stable tracking? 3) Can linguistic
information augment voice models?
authors: Isaac Bevers, Kaley Jenny, Rahul Brito, Jordan Wilke, Miles Silva, Fabio Catania
link:
url: ../speech_biomarkers
display: Project details
highlight: 1
news2:


- title: Detecting unilateral vocal fold paralysis
image: ../images/fig_speech_schematic_cropped.png
description: >
The aim of this project was to develop a model to detect unilateral vocal
fold paralysis from audio recording of voice.
authors: D Low, P Song, G Randolph, V Rao
link:
url: https://doi.org/10.1101/2020.11.23.20235945
display: Preprint
highlight: 1
news2:

- title: Subcortical anatomy of the auditory system
image: https://ndownloader.figshare.com/files/14418503/preview/14418503/preview.jpg
description: >
The aim of this project is to identify brainstem structures and their
connectivity. This is Kevin Sitek's NIH F31 project involving high resolution
imaging and analysis of _post mortem_ and _in vivo_ data.
authors: K Sitek, OF Gulban, F de Martino, GA Johnson, E Calabrese
link:
url: https://docs.google.com/presentation/d/1HeepU82sskD2VL62vcktGBSE5nl35toq9k47gKefBqc/edit#slide=id.p
display: Poster from OHBM 2019
highlight: 0
news2: <a href="https://www.biorxiv.org/content/10.1101/568139v2">Article preprint</a>

- title: Imaging genetics analysis of schizophrenia
image: ../images/OHBM_poster_model.png
description: >
This is a collaboration with the <a href="http://genus.mgh.harvard.edu/">Genus
Consortium</a> to apply multivariate data mining and visualizatin tools to
the GENUS dataset. An additional target is to support data harmonization in
multi-site studies. Key questions are: 1) Do multivariate deterministic and
probabilistic tools provide a more sensitive approach to detecting genetic
markers of brain structure and cognitive variation? 2) Can a common
vocabulary help organize and analyze multi-site data?
authors: D Burdinski, Y Sanchez-Araujo, K Batmanghelich, G Blokland, T Petryshen
link:
url: https://docs.google.com/presentation/d/14wvviEmK9FYyex6y8GqT-5w5wDdq02pjAF6wP5kSyvQ/edit
display: OHBM 2019 presentation
highlight: 1
news2: <a href="https://github.com/YSanchezAraujo/variational_lsrc">Analysis code</a>

- title: Using neurofeedback to reduce auditory hallucination in schizophrenia
image: https://cos.northeastern.edu/penlab/wp-content/uploads/2018/12/rtfMRI_update_final-1024x908.png
description: >
This is a collaboration with the <a href="https://cos.northeastern.edu/penlab/"
target="_blank">PEN Lab</a> to use realtime fMRI biofeedback to to increase
the positive diametric activity in patients with schizophrenia.
authors: >
S Whitfield-Gabrieli, C Bauer, K Okano, M Niznikiewicz, A van der Kouwe,
P Wighton
link:
url: https://cos.northeastern.edu/penlab/projects/real-time-fmri-neurofeedback/
display: Description at PEN Lab
highlight: 0
news2:

- title: Mental well-being platform
image: https://images.unsplash.com/photo-1588775841450-fc1aaefe1836?ixlib=rb-1.2.1&ixid=MXwxMjA3fDB8MHxwaG90by1wYWdlfHx8fGVufDB8fHw%3D&auto=format&fit=crop&w=708&q=80
description: >
The aim of this project is to create a platform outlining tasks that have been shown to improve well-being with the option of input by the user community.
The platform includes an optional study protocol to monitor the effects of performing the tasks over time.
The website will serve as the basis for future well-being studies.
authors: >
D Low, D Burdinski, A Dulski, K Wang
link:
url: https://mentalwellbeing.us/
display: Mentalwellbeing.us
highlight: 1
news2:

- title: Disease risk prediction from imaging genetics
image: ../images/undraw_medicine.png
description: >
The aim of this project is to harness both genetic and brain imaging data from the Adolescent Brain Cognitive Development Study
and the UK Biobank in order to design models that predict disease risk from genes and brain endophenotypes.
The project will explore to what extent incorporating intermediate phenotypes that are more closely tied to biology
and may capture environmental effects increases predictive ability compared to polygenic risk scores alone,
and what additional insights can be gained with this method (eg. new loci discovery, better mechanistic understanding, delineation of new disease subtypes).
authors: >
D Burdinski
link:
url:
display:
highlight: 1
news2:

- title: "Vocallect: Detecting Speech Biomarkers of Communication Disorders"
image: ../images/Vocallect Image.png
description: >
The purpose of this study is to understand and classify the impacts that communication disorders may have on speech production and acoustic quality. Subjects
will respond to questions regarding their current health, and provide sample voice recordings and free and read speech through a smartphone application and/or
web browser. By collecting and correlating self-reported symptoms with audio features, we intend to develop and validate a voice-based technology using signal
processing and machine learning that can be used for in-hospital and in-home monitoring of communication disorders, treatment, and recovery.
authors: K Nguyen
link:
url: ../vocallect
display: Project details
highlight: 1
news2:

- title: "Mumble Melody: Musically Modulated Auditory Feedback to Increase Fluency for People Who Stutter"
image: ../images/Mumble_Melody_logo.jpg
description: >
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38 changes: 0 additions & 38 deletions docs/_data/team_members.yml
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Expand Up @@ -23,14 +23,6 @@
number_educ: 1
education1: PhD Cognitive and Neural Systems, Boston University

- name: Daniel M. Low
photo: ../images/daniel_low_lo_fi.png
info: PhD Student
email: [email protected]
number_educ: 2
education1: MA Language & Communication Technologies, University of Groningen
education2: MS Cognitive Science, CIMeC, University of Trento

- name: Debbie Burdinski
photo: ../images/debbie.jpeg
info: MD-PhD Student, Harvard Medical School and MIT
Expand All @@ -53,14 +45,6 @@
number_educ: 1
education1: BS Bioengineering, University of Washington

- name: Gasser Elbanna
photo: ../images/Gasser.png
info: PhD Student
email: [email protected]
number_educ: 2
education1: M.Sc. in Neuroscience and Neuroengineering, EPFL
education2: B.Sc. in Systems and Biomedical Engineering, Cairo University

- name: Fabio Catania
photo: ../images/fabio_catania_photo.jpg
info: Postdoctoral research fellow, MIT
Expand Down Expand Up @@ -99,14 +83,6 @@
number_educ: 1
education1: B.S. in Neuroscience, Emmanuel College

- name: Sabeen Lohawala
photo: ../images/sabeen.png
info: MEng Student, MIT
email: [email protected]
number_educ: 2
education1: MEng in Computer Science, MIT
education2: B.S. in Computer Science, MIT

- name: Harsha Gazula
photo: ../images/non_descript_photo.png
info: Research Scientist
Expand Down Expand Up @@ -135,20 +111,6 @@
number_educ: 1
education1: Ph.D. in Electrical Engineering and Computer Science, KAIST, Korea

- name: Ahmed Zain
photo: ../images/ahmed_zain.jpeg
info: Undergraduate Researcher
email: [email protected]
number_educ: 1
education1: B.S. in Computer Science and Engineering, MIT

- name: Agathe Tournant
photo: //scholar.googleusercontent.com/citations?view_op=view_photo&user=cwcd3BIAAAAJ&citpid=2
info: Visiting M.S. student from ETH Zurich
email: [email protected]
number_educ: 1
education1: B.S. in Physics, EPFL

- name: Aaron Kanzer
photo: ../images/Aaron_Kanzer.png
info: Software Engineer
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30 changes: 16 additions & 14 deletions docs/_pages/speech_biomakers.md
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---
title: "Voice and Language Biomarkers for Mental Health"
title: "Voice and Language Biomarkers for Health"
layout: textlay
excerpt: "Speech biomarkers"
sitemap: false
permalink: /speech_biomarkers/
---

# Voice and Language Biomarkers for Mental Health
# Voice and Language Biomarkers for Health

<img src="{{ "/images/reddit_figure1_covid19_boolean.png" | prepend: site.baseurl | prepend: site.url}}" class="img-responsive" width="25%" style="float: right; margin: 0.8%; min-width: 350px" />

<br />

**Overall Aim:** To detect mental health symptoms from voice and language data
**Overall Aim:** To detect health symptoms from voice, language, and other sensor data

**Team Members:** Daniel Low, Debbie Burdinski, Satra Ghosh
**Team Members:** Isaac Bevers, Kaley Jenny, Rahul Brito, Jordan Wilke, Miles Silva, Fabio Catania

<br />

**Prior work:**

#### Detecting vocal fold paralysis and biases in voice data collection
Analyzing sustained vowel and read speech to detect unilateral vocal fold paralysis. Also exploring biases
in recording and comparing ML performance to that of clinician's ability to detect diagnosis from voice.

[Link to publication](https://journals.plos.org/digitalhealth/article?id=10.1371/journal.pdig.0000516)

**Collaborators:** Phil Song

<br />

Expand Down Expand Up @@ -47,13 +59,3 @@ Featured in [MIT News](https://news.mit.edu/2020/covid-19-impact-mental-health-1
**Collaborators:** Matt Nock, Walter Dempsey, Kelly Zuromski, Daniel Kessler, RallyPoint

<br />

#### Tracking longitudinal changes in voice and language using ecological momentary assessments
**Collaborators:** Kate Bentley, Joe Maimone, Daniel Coppersmith, Rebecca Fortrang, Alex Millner, Matt Nock

<br />

#### Tracking changes in speech during transcranial magnetic stimulation trials
**Collaborators:** Joan Camprodon

<br />

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