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188 public repositories
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PK-Sim® is a comprehensive software tool for whole-body physiologically based pharmacokinetic modeling
Physiologically Based Pharmacokinetic Models for Pregnant Women
Whole-body PBPK model of midazolam as CYP3A4 DDI victim drug
Updated
Jul 7, 2022
MATLAB
Modeling of published clinical Clarithromycin-Midazolam-DDI studies for model evaluation
Updated
Feb 5, 2024
MATLAB
Whole-body PBPK model of digoxin as P-gp DDI victim drug
Whole-body PBPK model of rifampicin as CYP3A4 and P-gp DDI perpetrator drug
Updated
Sep 23, 2024
MATLAB
Whole-body PBPK model of efavirenz as CYP3A4 perpetrator drug
Updated
Oct 11, 2021
MATLAB
Modeling of published clinical Clarithromycin-Digoxin-DDI studies for model evaluation
Modeling of published clinical Itraconazole-Digoxin-DDI studies for model evaluation
Modeling of published clinical Cimetidine-Carbamazepine DDI studies for model evaluation
Whole-body PBPK model of alfentanil as CYP3A4 DDI victim drug
Updated
Aug 29, 2022
MATLAB
Updated
Sep 13, 2024
MATLAB
Whole-body PBPK model of cimetidine (OCT2/MATE and CYP3A4 DDI perpetrator drug)
Updated
Feb 2, 2024
MATLAB
Whole-body PBPK model of fluvoxamine as CYP1A2 and CYP3A4 DDI perpetrator drug
Updated
May 6, 2022
MATLAB
Whole-body PBPK model of clarithromycin as CYP3A4 and P-gp DDI perpetrator drug
Updated
Oct 1, 2021
MATLAB
Whole-body PBPK model of triazolam
Updated
Oct 1, 2021
MATLAB
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