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# moPepGen: <u>M</u>ulti-<u>O</u>mics <u>Pep</u>tide <u>Gen</u>erator | ||
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[![Lifecycle:Maturing](https://img.shields.io/badge/Lifecycle-Maturing-007EC6)](https://img.shields.io/badge/Lifecycle-Maturing-007EC6) | ||
[![Tests](https://github.com/uclahs-cds/package-moPepGen/actions/workflows/tests.yaml/badge.svg)](https://github.com/uclahs-cds/package-moPepGen/actions/workflows/tests.yaml) | ||
[![Docker](https://img.shields.io/badge/docker-%230db7ed.svg?style=plastic&logo=docker&logoColor=white)](https://github.com/uclahs-cds/package-moPepGen/pkgs/container/mopepgen) | ||
[![Documentation](https://img.shields.io/static/v1?style=plastic&message=ReadTheDocs&color=2C4AA8&logo=ReadTheDocs&logoColor=FFFFFF&label=Documentation)](https://uclahs-cds.github.io/package-moPepGen/) | ||
[![License](https://img.shields.io/badge/License-GPL_v2-blue)](./LICENSE.txt) | ||
[![DOI:10.1101/2024.03.28.587261](https://zenodo.org/badge/DOI/10.1101/2024.03.28.587261.svg)](https://doi.org/10.1101/2024.03.28.587261) | ||
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moPepGen (multi-omics peptide generator) uses data from one or more omics experiments and calls variant peptides as custom databases for proteogenomic library search. | ||
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moPepGen takes genomic and transcriptomic variants such as single nucleotide variants (SNPs or SNVs), small insertions/deletions (indels), gene fusion, alternative splicing, RNA circularization and RNA editing events, and generates noncanonical peptides affected by the variants. | ||
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## Overview | ||
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![graphic-abstract](img/graphic-abstract.png) | ||
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## Citation | ||
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1. Zhu, C. et al. moPepGen: Rapid and Comprehensive Proteoform Identification. 2024.03.28.587261 Preprint at https://doi.org/10.1101/2024.03.28.587261 (2024). |