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New Long Read Giraffe parameters#4524

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adamnovak merged 7 commits intomasterfrom
lrg-params
Feb 14, 2025
Merged

New Long Read Giraffe parameters#4524
adamnovak merged 7 commits intomasterfrom
lrg-params

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Changelog Entry

To be copied to the draft changelog by merger:

  • vg giraffe has new hifi and r10 preset parameters that improve speed, are mostly neutral on calling accuracy, but add more wrong MAPQ 60 HiFi reads.
  • Zip code ancestor orientation bugfix for vg giraffe: all minimizer and zipcode files will need to be re-generated to take advantage of it.

Description

This changes the Long Read Giraffe parameters to increase speed, balance performance across the sampled and non-sampled graphs, and (sadly) add a bunch of to-be-diagnosed wrong MAPQ 60 HiFi reads.

It also has @xchang1's fix for a problem with zip code tree orientations.

@adamnovak adamnovak merged commit 1629b09 into master Feb 14, 2025
@faithokamoto faithokamoto deleted the lrg-params branch August 21, 2025 19:01
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2 participants