security update

Gemfile.lock

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     rb-fsevent (0.11.2)
     rb-inotify (0.10.1)
       ffi (~> 1.0)
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+    rexml (3.2.6)
     rouge (4.1.2)
     ruby2_keywords (0.0.5)
     safe_yaml (1.0.5)

_site/index.html

@@ -392,7 +392,7 @@ <h2 class="username">Vitor Sudbrack</h2>
 
 <p>The influence of these evolutionary processes on TRs is well understood in large haploid populations where individuals mate randomly. But many organisms are capable of selfing, which leads to inbreeding and an excess of homozygosity with relevant consequences for the evolutionary processes that shape variation in TRs. In this project, we use mathematical modeling to investigate the evolutionary dynamics of homologous TRs under the joint actions of purifying selection, amplification, unequal recombination, and genetic drift in a population of partially selfing diploids.</p>
 
-<p>We find that the equilibrium distribution of TRs in the population depends on the interaction between unequal recombination and selfing. When the selfing rate is low and homologous sequences within individuals tend to be different, unequal recombination reduces variation. However, when selfing is common and homologous sequences within individuals are more similar, unequal recombination increases the variation in TRs.  In addition, because selfing increases variation between individuals relative to within individuals, purifying selection tends to be stronger in selfers compared to outcrossers. As a result, selfers have on average shorter TRs, in spite of experiencing increased genetic drift.</p>
+<p>With my PhD supervisor Charles Mullon, we find that the equilibrium distribution of TRs in the population depends on the interaction between unequal recombination and selfing. When the selfing rate is low and homologous sequences within individuals tend to be different, unequal recombination reduces variation. However, when selfing is common and homologous sequences within individuals are more similar, unequal recombination increases the variation in TRs.  In addition, because selfing increases variation between individuals relative to within individuals, purifying selection tends to be stronger in selfers compared to outcrossers. As a result, selfers have on average shorter TRs, in spite of experiencing increased genetic drift.</p>
 
 
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@@ -456,7 +456,7 @@ <h2 class="username">Vitor Sudbrack</h2>
       <div class="content">
         <p>In subdivided populations, different ecological processes drive intraspecific phenotypic variation at different spatial scales. While spatial heterogeneity promote distinct morphs in different patches leading to local adaptation, negative-frequency dependent selection arising from local competition favours polymorphism within patches. The emergence and maintenance of these different phenotypes is not straightforward when traits are polygenic as hybridization breaks up adaptive allele combinations. In this case, selection acts on genetic architecture to concentrate allelic effects onto as few independently segregating loci as possible. This concentration may be achieved via different genetic mechanisms such as amplifiers of allele effect size or suppressors of recombination, but it remains unclear whether selection favours different mechanisms in different ecological settings.</p>
 
-<p>In this project, together with Ewan O. Flintham, we use computational models to study the evolution of a trait’s genetic architecture through various modifiers of allelic effects and of recombination, varying the extent to which polymorphism in the trait is favoured by spatial heterogeneity or local competition. We show that owing to more frequent hybridisation, local competition exerts stronger selection on genetic architecture than spatial heterogeneity. Furthermore, these different ecological processes favour different levels of genetic dominance and different patterns of recombination. In particular, local adaptation often involves large regions of recombination suppression when local competition generally sees multiple smaller regions scattered across the genome.</p>
+<p>In this project, together with my PhD supervisor Charles Mullon and the postdoc at out lab Ewan O. Flintham, we use computational models to study the evolution of a trait’s genetic architecture through various modifiers of allelic effects and of recombination, varying the extent to which polymorphism in the trait is favoured by spatial heterogeneity or local competition. We show that owing to more frequent hybridisation, local competition exerts stronger selection on genetic architecture than spatial heterogeneity. Furthermore, these different ecological processes favour different levels of genetic dominance and different patterns of recombination. In particular, local adaptation often involves large regions of recombination suppression when local competition generally sees multiple smaller regions scattered across the genome.</p>
 
 
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