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MichaelClerx authored Jun 15, 2022
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# Models of the cardiac L-type calcium current: a quantitative comparison
This repository contains all protocols, models, codes, figure generating files, and animation for the comparison of ICaL models.

An interactive view of our main results can be viewed on the [Cardiac Electrophysiology Web Lab](https://scrambler.cs.ox.ac.uk/stories/8).

- [Example Models](https://github.com/CardiacModelling/ical-review/blob/master/Example_Models.ipynb) gives the equations for a Hodgkin-Huxley model and a Markov model.
- [Models](https://github.com/CardiacModelling/ical-review/tree/master/Models) contains the CellML implementations for all models used (quantitatively) in this study, with links to the original sources and an overview of major [data sources](https://github.com/CardiacModelling/ical-model-comparison/blob/master/Models/data.md) used in their construction.
- [Figure 1](https://github.com/CardiacModelling/ical-model-comparison/blob/master/Data_Analysis/AP_CaT_Clamp/AP_Clamp_protocol/figure1.pdf)
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## Software
- **Web Lab** Simulations were run using the Cardiac Electrophysiology Web Lab.
See the resultant experiment matrix at [https://bit.ly/LtypeCa](https://bit.ly/LtypeCa).
An interactive overview of our results is [available here](https://scrambler.cs.ox.ac.uk/stories/8).
Find out more about Web Lab from [doi: 10.1016/j.bpj.2015.12.012](https://dx.doi.org/10.1016%2Fj.bpj.2015.12.012).
- **Python** The code requires Python (either 2.7 or 3.3+) and the Python dependencies Myokit, and `pandas`.
The other dependencies can be installed with `pip`, e.g. `pip install myokit` (or `pip3 install myokit` for some python 3 environments).
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