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Added parallelization for the data objects in resampling for noise
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Kristen Naegle committed Jun 12, 2018
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121 changes: 73 additions & 48 deletions examples/Ensembles_Across_Experimental_Noise-parallel.ipynb

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11 changes: 11 additions & 0 deletions examples/Ensembles_Across_Experimental_Noise.ipynb
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"# Create resampling of available replicate data to explore effects of noise"
]
},
{
"cell_type": "markdown",
"metadata": {},
"source": [
"This is similar to the example in Sloutsky, R., Jimenez, N., Swamidass, S. J. & Naegle, K. M. Accounting for noise when clustering biological data. Brief. Bioinform. 14, 423–36 (2013) -- we resample each data point according to a Guassian distribution defined by the mean and standard deviation of the measured data. \n",
"\n",
"This example is phosphoproteomic dataset of epithelial cells stimulated with a growth factor and measured immediately afterward at seven time points in the first 32 minutes, specifically [0, 1, 2, 4, 8, 16, 32]. It was downloaded from [ProteomeScout](https://proteomescout.wustl.edu/experiments/1381) and published in: Wolf-Yadlin, A., Hautaniemi, S., Lauffenburger, D. A. & White, F. M. Multiple reaction monitoring for robust quantitative proteomic analysis of cellular signaling networks. Proc. Natl. Acad. Sci. U. S. A. 104, 5860–5 (2007). \n",
"\n",
"Compare this to the [example with parallelization]() "
]
},
{
"cell_type": "code",
"execution_count": 1,
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