Version 10.0
This release contains the OSP PBPK substance model library.
All models are published as a PK-Sim project model file along with a model evaluation report.
The project model files and evaluation reports of this release are created with OSP 10 and are available here.
Release Notes
Notes are listed below for new or updated model files/evaluation reports. All other model files/evaluation reports are unchanged compared to the previous release.
New models
Amikacin
added based on version 1.2
Fluconazole
added based on version 1.0
Montelukast
added based on version 1.2
Raltegravir
added based on version 1.2
Sufentanil
added based on version 1.2
Vancomycin
added based on version 1.2
Updates
Alfentanil
updated based on version 2.2
- Model updated to reflect the changes in PK-Sim 10
Alprazolam
updated based on version 1.1
- Model updated to reflect the changes in PK-Sim 10
Cimetidine
updated based on version 1.1
- Model updated to reflect the changes in PK-Sim 10
Clarithromycin
updated based on version 1.2
- Model updated to reflect the changes in PK-Sim 10
Efavirenz
updated based on version 1.1
- Model updated to reflect the changes in PK-Sim 10
Erythromycin
updated based on version 1.2
- Model updated to reflect the changes in PK-Sim 10
Itraconazole
updated based on version 1.3
- Model updated to reflect the changes in PK-Sim 10
Midazolam
updated based on version 1.1
- Model updated to reflect the changes in PK-Sim 10
Rifampicin
updated based on version 1.2
- Model updated to reflect the changes in PK-Sim 10
Triazolam
updated based on version 1.1
- Model updated to reflect the changes in PK-Sim 10
Verapamil
updated based on version 1.2
- Model updated to reflect the changes in PK-Sim 10