Version 9.1.1

This release contains the OSP PBPK substance model library.
All models are published as a PK-Sim project model file along with a model evaluation report.
The project model files and evaluation reports of this release are created with OSP 9.1 and are available here.

Release Notes

Notes are listed below for new or updated model files/evaluation reports. All other model files/evaluation reports are unchanged compared to the previous release.

New models

Cimetidine

added based on version 1.0

Updates

Alfentanil

updated based on version 2.1

• Removal of unneeded observed dataset

Clarithromycin

updated based on version 1.1

• Editorial bug fix in links to references

Erythromycin

updated based on version 1.1

• Editorial bug fixes in static text blocks

Fluvoxamine

updated based on version 1.1

• Editorial bug fix in links to references in static text block

Itraconazole

updated based on version 1.2

• Remove unneeded entry option for organ permeability of itraconazole

Rifampicin

updated based on version 1.1

• Editorial bug fix in links to references in static text blocks

Verapamil

updated based on version 1.1

• Editorial bug fix in links to references in static text blocks

Triazolam

• correct pdf document added to exchange corrupt pdf file