Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Adding version 2.0 link #8

Open
wants to merge 1 commit into
base: master
Choose a base branch
from
Open
Changes from all commits
Commits
File filter

Filter by extension

Filter by extension

Conversations
Failed to load comments.
Loading
Jump to
Jump to file
Failed to load files.
Loading
Diff view
Diff view
2 changes: 2 additions & 0 deletions README.md
Original file line number Diff line number Diff line change
@@ -1,5 +1,7 @@
# GeneSetCluster

GeneSetCluster version 2.0 is available: https://github.com/TranslationalBioinformaticsUnit/GeneSetCluster2.0

Gene-set analysis (GSA) tools aim to provide biological context by identifying gene-sets associated with a given trait or traits of interest. Gene-set analysis tools are frequently gene-centric, using as input results from studies using RNA-seq or microarrays data (e.g. Ingenuity or GSEA among many others), but it has also been adapted for interval-based analysis derived from data-types such as DNA methylation or ChIP/ATAC-seq.

Gene-sets are derived from knowledge bases which group genes on the basis of shared biological or functional properties; GSA tools provide, as a result, a list of significant gene-sets. However, while these results are useful for the researcher in the identification of major biological insights, they may be complex to interpret because many gene-sets have largely overlapping gene content or because the result consists of a large number of gene-sets making it complicated to identify the major biological insights.
Expand Down