Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Added L4 IT MOp #1011

Closed
wants to merge 3 commits into from
Closed
Changes from all commits
Commits
File filter

Filter by extension

Filter by extension

Conversations
Failed to load comments.
Loading
Jump to
Jump to file
Failed to load files.
Loading
Diff view
Diff view
77 changes: 35 additions & 42 deletions src/ontology/cl-edit.owl
Original file line number Diff line number Diff line change
Expand Up @@ -2473,23 +2473,12 @@ Declaration(Class(obo:CL_4023038))
Declaration(Class(obo:CL_4023040))
Declaration(Class(obo:CL_4023041))
Declaration(Class(obo:CL_4023042))

Declaration(Class(obo:CL_4023046))


Declaration(Class(obo:CL_4023047))
Declaration(Class(obo:CL_4023048))
Declaration(Class(obo:CL_4023049))


Declaration(Class(obo:CL_4023050))


Declaration(Class(obo:CL_4023048))

Declaration(Class(obo:CL_4023047))




Declaration(Class(obo:CL_4023051))
Declaration(Class(obo:CP_0000000))
Declaration(Class(obo:CP_0000025))
Declaration(Class(obo:CP_0000027))
Expand Down Expand Up @@ -27748,7 +27737,6 @@ SubClassOf(obo:CL_4023042 obo:CL_4023013)

# Class: obo:CL_4023046 (L6b subplate glutamatergic neuron of the primary motor cortex (Mus musculus))


AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023046 "An excitatory glutamatergic neuron transcriptomically related to the CT subclass, with a soma preferentially located in the bottom of L6 of the primary motor cortex.")
AnnotationAssertion(<http://purl.org/dc/elements/1.1/creator> obo:CL_4023046 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023046 <http://purl.obolibrary.org/obo/cl#BDS_subset>)
Expand All @@ -27757,6 +27745,29 @@ SubClassOf(obo:CL_4023046 obo:CL_4023038)
SubClassOf(obo:CL_4023046 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))
SubClassOf(obo:CL_4023046 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_4023047 (L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.343129") obo:IAO_0000115 obo:CL_4023047 "An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 2/3.")
AnnotationAssertion(<http://purl.org/dc/elements/1.1/creator> obo:CL_4023047 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023047 "L2/3 IT MOp (Mus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023047 <http://purl.obolibrary.org/obo/cl#BDS_subset>)
AnnotationAssertion(rdfs:label obo:CL_4023047 "L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus)")
SubClassOf(obo:CL_4023047 obo:CL_4023040)
SubClassOf(obo:CL_4023047 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))
SubClassOf(obo:CL_4023047 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_4023048 (L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023048 "An intratelencephalic-projecting glutamatergic with a soma located in upper L5 of the primary motor cortex. These cells have thin untufted apical dendrites.")
AnnotationAssertion(<http://purl.org/dc/elements/1.1/creator> obo:CL_4023048 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023048 "ILX:0770174")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023048 "L4/5 IT MOp (Mus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023048 <http://purl.obolibrary.org/obo/cl#BDS_subset>)
AnnotationAssertion(rdfs:label obo:CL_4023048 "L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus)")
SubClassOf(obo:CL_4023048 obo:CL_4023040)
SubClassOf(obo:CL_4023048 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))
SubClassOf(obo:CL_4023048 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_4023049 (L5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023049 "An intratelencephalic-projecting glutamatergic neuron with a soma found in L5 of the primary motor cortex.")
Expand All @@ -27771,7 +27782,6 @@ SubClassOf(obo:CL_4023049 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_1009

# Class: obo:CL_4023050 (L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus))


AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:9236245") obo:IAO_0000115 obo:CL_4023050 "An intratelencephalic-projecting glutamatergic neuron with a soma found in L6 of the primary motor cortex. These cells are short untufted pyramidal cells, which could be stellate or inverted.")
AnnotationAssertion(<http://purl.org/dc/elements/1.1/creator> obo:CL_4023050 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023050 "ILX:0770158")
Expand All @@ -27782,32 +27792,15 @@ SubClassOf(obo:CL_4023050 obo:CL_4023040)
SubClassOf(obo:CL_4023050 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))
SubClassOf(obo:CL_4023050 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_4023048 (L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023048 "An intratelencephalic-projecting glutamatergic with a soma located in upper L5 of the primary motor cortex. These cells have thin untufted apical dendrites.")
AnnotationAssertion(<http://purl.org/dc/elements/1.1/creator> obo:CL_4023048 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023048 "ILX:0770174")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023048 "L4/5 IT MOp (Mus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023048 <http://purl.obolibrary.org/obo/cl#BDS_subset>)
AnnotationAssertion(rdfs:label obo:CL_4023048 "L4/5 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus)")
SubClassOf(obo:CL_4023048 obo:CL_4023040)
SubClassOf(obo:CL_4023048 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))
SubClassOf(obo:CL_4023048 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))

# Class: obo:CL_4023047 (L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "DOI:10.1101/2020.10.19.343129") obo:IAO_0000115 obo:CL_4023047 "An intratelencephalic-projecting glutamatergic neuron with a soma found in cortical layer 2/3.")
AnnotationAssertion(<http://purl.org/dc/elements/1.1/creator> obo:CL_4023047 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023047 "L2/3 IT MOp (Mus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023047 <http://purl.obolibrary.org/obo/cl#BDS_subset>)
AnnotationAssertion(rdfs:label obo:CL_4023047 "L2/3 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus)")
SubClassOf(obo:CL_4023047 obo:CL_4023040)
SubClassOf(obo:CL_4023047 ObjectSomeValuesFrom(obo:RO_0002100 obo:UBERON_0001384))
SubClassOf(obo:CL_4023047 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_10090))



# Class: obo:CL_4023051 (L4 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus))

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:33184512") obo:IAO_0000115 obo:CL_4023051 "An intratelencephalic-projecting glutamatergic neuron that is located in the boundary between L2/3 and L5 of the primary motor cortex. These cells have diverse morphologies with some pyramidal and some stellate cells.")
Copy link
Contributor

Choose a reason for hiding this comment

The reason will be displayed to describe this comment to others. Learn more.

This strikes me as a heterogenous grouping class that only makes sense in the context of single cell transcriptomics clustering. I wonder whether we should make that explicit + define using markers (RF markers could work well for this). I think worth holding off for further discussion.

AnnotationAssertion(<http://purl.org/dc/elements/1.1/creator> obo:CL_4023051 <http://orcid.org/0000-0001-7258-9596>)
AnnotationAssertion(oboInOwl:hasDbXref obo:CL_4023051 "ILX:0770172")
AnnotationAssertion(oboInOwl:hasExactSynonym obo:CL_4023051 "L4 IT MOp (Mus)")
AnnotationAssertion(oboInOwl:inSubset obo:CL_4023051 <http://purl.obolibrary.org/obo/cl#BDS_subset>)
AnnotationAssertion(rdfs:label obo:CL_4023051 "L4 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (Mus musculus)")
SubClassOf(obo:CL_4023051 obo:CL_4023040)

# Class: obo:CP_0000000 (neutrophillic cytoplasm)

Expand Down Expand Up @@ -27905,4 +27898,4 @@ SubClassOf(obo:D96882F1-8709-49AB-BCA9-772A67EA6C33 obo:GO_0005634)


SubClassOf(Annotation(oboInOwl:hasDbXref <https://github.com/obophenotype/cell-ontology/issues/757>) ObjectIntersectionOf(obo:CL_0000540 ObjectSomeValuesFrom(obo:RO_0002162 obo:NCBITaxon_7742)) ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000031))
)
)