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Perl script for generating genotype calls for unrelated durum wheat samples assayed using the Illumina iSelect 90K SNP bead chip array

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plantinformatics/Durum_iSelect_90kSNP_GenotypeCalling

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Durum_iSelect_90kSNP_GenotypeCalling

Perl script for generating genotype calls for unrelated durum wheat samples assayed using the Illumina iSelect 90K SNP bead chip array

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Call_90K_genotypes_For_Unrelated_Samples.pl

This scripts generates genotype calls for unrelated samples assayed using the iSelect 90K wheat SNP bead chip.

Genotype calls (A and B, where A denotes adenosine or thymine; and B denotes cytosine and guanine) are generated for 
clusters that unambigiously associate with genetically map loci. 

Options for running this perl script

  -c   Folder path and name of file containing cluster information; *_ClusterToMappedLoci.txt
  
  -f   Folder path and name of FullDataTable exported from GenomeStudio
       Format: Text-delimited <SNPindex><SNPname><Sample1.theta><Sample1.normR><Sample2.theta><Sample2.normR> etc
	   
  -d   Distance limit for cluster assignment (in standard deviations). Default 2
  
  -s   Confidence score for genotype call(value between 0 and 1, where 1 is highest) Default 0.7
  
  -r   Only report polymorphic SNPs in *_GENO_InformativeSNPtable and *_GENO_InformativeSNPreport
       when they have MAF > user-specified value. Use 0 to report all SNPs
	   
  -o   Folder path and name of output file

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Perl script for generating genotype calls for unrelated durum wheat samples assayed using the Illumina iSelect 90K SNP bead chip array

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