CRISP-DIA is a software for liquid chromatography-tandem mass spectrometry (LC-MS/MS) based proteomics data processing, which enables accurate and reliable quantification for data-independent acquisition (DIA) proteomics.

Principles and algorithms are detailed in:

Yan B., et al. Data-Driven Tool for Cross-Run Ion Selection and Peak-Picking in Quantitative Proteomics with Data-Independent Acquisition LC-MS/MS, Analytical Chemistry, 2023, 95, 16558-16566, DOI: 10.1021/acs.analchem.3c02689.