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This version is a Python implementation (with GUI) of CRISP-DIA. The Matlab Environment, which was necessary for the previous versions, is no longer needed.
Direct processing of .raw and .wiff files is supported additionally (converting DIA data files to .mzML using MSConvert is optional now).
If staggered (multiplexed) DIA isolation windows are used, they will be demultiplexed automatically.
Maxquant library (msms.txt) can be converted to a .csv file (for CRISP-DIA processing) using the Manu ‘Convert’->‘Convert Maxquant msms.txt to Library’.
‘iRT_PeptideMSspec’ can be created from a .csv library file using the Manu ‘Convert’->‘Create iRT_PeptideMSspec file from Library’.
The processing speed is a little slower than version 1.0.1, which is expected to be improved in the next version.