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Scoring methods
Julian Uszkoreit edited this page Mar 7, 2014
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Whether a higher or a lower protein score is better, depends directly on the scoring method. For "Additive Scoring", a higher score is assumed to be better. For both other scorings, a lower score is better. Note, that the protein score is not the product of the PSM scores, but the sum of the logs for numerical safety, therefore the scores are mainly below zero.
human readable name | short | explanation |
---|---|---|
Additive Scoring | scoring_additive | Sums up the scores of PSMs for the protein score. Usable when scores (instead of properties/e-values) are used, like Mascot ion score, SEQUEST XCorr |
Multiplicative Scoring | scoring_multiplicative | Multiplies the scores of PSMs for the protein score. Usable when properties/e-values (instead of scores) are used, like Mascot or X!Tandem expect value orthe FDR Score |
Geometric Mean Scoring | geometric_mean_scoring | Calculates the geometric mean of the PSMs' scores for the protein score. Usable when properties/e-values (instead of scores) are used. |